Boilerplate Text for Training Grants

For training grant directors, you are welcome to personalize these descriptions by substituting the name of your program for our resource names (e.g., “[Program Name] Seminars” instead of “Edge Seminars”).

At the end is a list of commonly requested percentages and numbers relating to career development at Vanderbilt.

Edge for Scholars at Vanderbilt provides an integrated career development program for all clinician-scientists, regardless of their scope of research, and for PhD scientists engaged in translational or clinical research. We are the home of training programs such as those proposed in this application to support CTSA KL2 scholars and TL1 trainees and overall serve the needs of more than 110 career development awardees and 190 pre- and postdoctoral trainees working in translational science. We coordinate most of the educational and career development activities described in the grant that are outside traditional graduate programs. They include Edge Scholars, Edge Seminars, The Newman Society, Annual Translational Research Forum, Grant Pacing Workshops, Funded Grants Library, Mock Study Section, and Flight Tracker. We constantly collect and respond to feedback from trainees, early career faculty, and mentors. We compile data about our outcomes, examine them in the context of national outcomes data, and strategize, based on our local needs and national best practices, about how to implement a continuously evolving panel of exceptional resources to promote the careers of all our scientists across the arc of their careers.

Edge for Scholars Funded Grants Repository. This protected grants library provides exemplars of successful grantsmanship. The repository includes summary statements and resubmissions from over 440 grants that span the range of translational research from drug targeting to community interventions and from epidemiologic investigations to qualitative studies. We host 154 R01s, along with 41 R21s and R03s, 6 VA Merit awards, 4 R34s, 3 R35s, 3 R36s, 2 R18s, an R61, and two DP1s. Our 135 K awards include various K01s, K08s, K23s, and 5 K24 mid-career mentoring grants, as well as 4 VA CDAs, and foundation awards such as AHA career development and Doris Duke Foundation Clinical Scientist Development awards. As well, we host 24 F30s, 20 F31s or equivalent foundation predoc fellowships, 11 F32s, and 1 F99. The library includes 12 examples of successful NIH loan repayment applications and 12 examples of large institutional grants such as U01s, as well as 3 PCORI grants.

Grant Pacing Workshops. This program weds introduction to project management skills to the steps required to produce the varied components required for successful grant application. Groups of no more than 18 investigators convene for two half-day workshops 16 and 14 weeks in advance of the coming federal grant deadline. In the first session they learn and apply skills in creating project timelines, identifying dependent components, and mapping “swim lanes” for major grant sections (budget and justification, scientific text, letters of support, human subjects, etc.) to indicate process flow and contingencies. Participants are strongly encouraged to build resources such as Studios and Edge Reviews into their timelines. The second workshop is also a half-day and includes individualized experience with tools for developing activity-based project budgets as well as strategies for enhancing grants with key types of tables and figures, and refining grant components from the reviewer’s perspective with examples from actual grants.

Internal Study Section (Edge Review). For over a decade our CTSA-supported internal grant review process has followed NIH study section format. Researchers submit their applications for review six weeks prior to NIH due dates. Following review, investigators receive summary statements in the NIH format as well as a video file of the session. Reviews include 1) all three major NIH standing submission deadlines as well as the three HIV/AIDS dates, 2) all K and R awards for all faculty who wish to use the service, as well as F awards for graduate students and postdocs, and 3) assignment of reviewers through use of a database that catalogues content and methods expertise of 427 federally funded investigators. Applicants for Edge Reviews complete a checklist of content and methods related to their grant for review, and we use optimization software to obtain an ideal match for first, second, and third reviewers. Between May 2011 and January 2024 (most recent Edge Review date for which grant would have known award), 59.4% of the 593 submissions reviewed have been funded.

Workshop and Other Opportunities. We provide:

• Manuscript Sprints, which provide peer accountability groups and review for authors to push toward completion of a manuscript within six weeks.
• Annual Translational Research Forum features more than 10 plenary talks by investigators. Speakers are former Vanderbilt and Meharry K awardees who have recently received R01 or equivalent funding. A poster competition introduced in 2016 drew 136 abstracts for consideration this year. Winners from the poster session receive travel awards to a professional meeting.
• Membership in the Newman Society is granted to all current K or equivalent awardees at Vanderbilt and Meharry (n=130). All members attend this monthly career development seminar. K alumni also take advantage of these forums. Topics for recent seminars and workshops include avoiding authorship woes, establishing an academic brand, leading teams, communication skills, negotiation, readiness for R award, and stress management. Many of the topics also carry Responsible Conduct of Research credit hours.
• Edge Career Development Seminars bring together trainees with translational career aspirations from more than 30 T32s (each program identifies two or three trainees), clinical research fellowships, the MSCI, the MPH, and the graduate programs described above. Both pre- and postdoctoral trainees attend. Those moving towards K applications also take advantage of these forums. Topics include skills in time management, communication, laboratory and personnel management, negotiation, authorship, and stress management aimed at enhancing the career development of new scientists. Many of the topics also carry responsible conduct of research credit hours. The goal is to provide formal career development resources, and an informal peer group, for all scientists early in their research careers. Lunch is provided and attendance tracked.
• Studios allow investigators a 1.5-hour meeting with a panel of expert consultants coordinated by VICTR staff. Scheduling, distributing materials in advance, providing a moderator, and soliciting feedback from participants is coordinated for the scholar so that s/he can best focus on preparing for the session and absorbing the guidance obtained from the review and advice on specific aspects of the research. Focus varies based on the needs of the researcher and includes hypothesis generation based on novel findings, review of aims and methods, critique of full proposals, manuscript review for high profile publications or contentious topics, troubleshooting research underway, and assessment of translational potential.
• Biostatistics Clinics are provided through the CTSA core and provide daily free sessions to which researchers can bring questions about analyses, whether it’s crunching numbers, designing new studies, applying for grants, or just theorizing. Investigators at any level may bring data or specific challenges for discussion with the biostatistics faculty. Often very practical assistance is provided such as: demonstration of analysis techniques with the data in question, new connections with consultants, reframing of study design, or derivation and discussion of power calculations.
• Pilot Funding allows researchers to request up to $100,000 in funding for pilot projects, with smaller amounts being granted within days to ensure no loss of momentum. In this funding year, 120 awards were given (success rate of 74%), 98 or 81.7% of which were to early career researchers.
• Edge Conversations occur quarterly and bring together informal groups of mentors and mentees to discuss books from business, psychology, and other genres selected for “actionable intel” on career development topics. Moderators have included Dr. Hartmann, Dr. Reed Omary, and Dr. Benjamin Tingey of Atrium Health. We took these local book clubs both virtual and national this year with the launch of the Edge Conversations Facebook group, which follows the local schedule and has over 100 members. Examples of selections include Whistling Vivaldi by Steele, Black Death at the Golden Gate: The Race to Save America from the Bubonic Plague by Randall, Multipliers by Wiseman, Atomic Habits by Clear, Getting to Yes by Fisher and Ury, Collaboration by Hansen (a Harvard Business Press offering), Resonate: Presenting Visual Stories that Transform Audiences by Duarte, Resilience by Greitens, and Getting Things Done: The Art of Stress Free Productivity by Allen.
• Analog Lending Library provides copies of books for Conversations as well as for general use. The library stocks more than 200 titles and can be accessed at seminars or via campus mail. Topics range from time management and productivity to writing skills, leadership to creativity, and more.
• Kaizen offers rigor, reproducibility and transparency education in a gamified setting. Scholars from predoc to early career are placed on teams and collect points and badges by reading assigned articles and answering questions about the reading. The University of Alabama at Birmingham’s CCTS developed the application and we piloted it in 2019 with 48 early career scholars from around the Vanderbilt campus. 100% of those who evaluated the platform agreed it was an attractive way to document the requirement for this type of learning, and many suggested other areas in which it could be used, such as responsible conduct of research, IRB requirements, and statistic concepts. Along with UAB, we launched a national game in February 2020, which promoted and recruited over 150 players via Edge for Scholars’ thriving social media outlets.
• Mentee-Mentor Agreement uses an interactive online approach to initiate and revisit the important conversations that are building blocks for a solid mentee-mentor relationship at any career stage. A mentee answers questions to help align expectations like shared goals, milestones, resources, and communication plan in order to frame discussions with a mentor. Mentee-mentor pairs are prompted to adjust the agreement on a regular basis.

COMMONLY REQUESTED NUMBERS

Current number of K/CDA awardees at Vanderbilt: Fluctuates as grants begin and end, but generally around 130

K-to-R conversion percentage for Vanderbilt: Also fluctuates as grants are awarded, but typically sits at 70%. Current n=301. Excludes those still on a K or similar award, as well as those who have left Vanderbilt without converting.

Conversion from internal K awards (VFRS) to extramural awards:

* Excludes those currently on internal K or KL2.

For those who have reached the end of their extramural K or who went straight to R01, the percentage who have received an R01 or equivalent is 62.8% (n=145).

Edge Review success rates:

Between May 2011 and January 2024 (most recent Edge Review date for which grant would have known award), 59.3% of the 593 submissions reviewed have been funded.

Of those who submitted a K-type grant for review during this time, 68.9% (n=264) received grant support thereafter. (Grant support includes an individual K or VA CDA, a foundation career development award, a place on a K12, or other type of grant such as R01.)